Prehospital Care of Severe Hyperkalemia
Dialysis centers and renal patients across the county activate EMS for a variety of concerning signs and symptoms either before, during or after dialyzing. The most common cases involve chest pain and dyspnea, however the etiology of these symptoms often involves hyperkalemia. Elevated levels of K+ can cause lethal arrhythmias and the management of these patients occasionally may require going above and beyond ACLS treatment of chest pain.
With any patient who presents with chest pain, managing airway, breathing, and circulation are obviously paramount and morphine/fentanyl, oxygen, nitroglycerin, aspirin (M.O.N.A), and early 12 lead ECGs are the first line treatment indications. If a 12 lead shows tall and peaked T waves, what does this mean for us in the back of an ambulance? This abnormal ECG indicates hyperkalemia, a true medical emergency, and our goal is to enhance the cellular uptake of potassium while stabilizing the myocardial cell membrane. Emergent dialysis is the definitive treatment, but we can help the patient with a few medications carried on Marion County ambulances.
Sample Case: You are dispatched to a residence for chest pain. Upon arrival you find a 45 year old black male who just returned from a long weekend trip out of town. His past medical history includes: atherosclerosis, acute renal failure and requires dialysis 3 times a week. The patient states he missed his last dialysis appointment 3 days ago and now complains of substernal chest pain 8/10, radiating to both arms and neck. The onset was gradual and while he was at rest. This sounds like a classic cardiac case right? Upon further exam his vitals are 110/58, heart rate of 42, and a respiratory rate of 14. His 12 lead ECG shows sinus bradycardia with no ST segment elevation, however you note markedly peaked T waves that are taller than the QRS complex. He is lethargic and diaphoretic. After first line cardiac treatments, he shows no signs of improvement and his pain is not relieved by nitro. His vitals remain unchanged. What are the options here? We need to treat his heart rate, but atropine is not an option as it’s an anticholinergic and increases oxygen demand on the heart. Since he is complaining of chest pain, we would not want to possibly increase cardiac ischemia. Transcutaneous pacing could be an option, however, his blood pressure is fine and his GCS is 15.
It’s now time to get creative with what we have on hand to treat this patient until he can be dialyzed. Under the current Marion County protocols, we have 3 medications that can be useful in this case in addition to our frontline ACS drugs. These medications are standing orders for a dialysis patient with wide complex rhythms associated with hypotension or refractory v-fib, but this patient doesn’t meet that criteria and we don’t want him to meet this criteria! If we can prevent a lethal arrhythmia, lets give that a go. It’s time to get on the radio and request orders for 1 gram of calcium chloride (slow IVP, to help shift the K+ intracellularly and stabilize the myocardial cell membrane), 100 mEq of sodium bicarbonate IV (if lung sounds are clear), and 5 mg albuterol treatments for the duration of the transport (the bicarb and albuterol will help cellular uptake of K+). Please note: DO NOT push calcium and bicarb through the same line.
In summary, get a good complete history on every patient and use this to your advantage. If they are a dialysis patient, start thinking a few steps ahead and give them every advantage for a favorable outcome. Always know the alternative uses for the medications we carry. The alternate uses may not be in the protocols, but we can always call for orders. The complex hyperkalemic patient can go south very quickly, so anticipate, react, and use your head.
Please let me know about your hyperkalemia cases, your treatments, and the patient’s outcomes.
References:
Bledsoe, B. E. (2007) Essentials of Paramedic Care
Verive, M. J. (2010). Hyperkalemia: Treatment & Medication. eMedicine. Retrieved from http://emedicine.medscape.com/article/907543-treatment
Indianapolis Metropolitan Area EMS Protocols 2010 Version


